# AlphaGenome MCP Server

> Use this tool when you need to analyze genomic variants and predict their impact on gene function, or discover regulatory elements in DNA sequences. The AlphaGenome MCP Server takes in genomic data and returns variant scores and predictions, enabling researchers to identify potential disease-causing mutations. Ideal for use in bioinformatics and genomics research, this tool streamlines variant analysis and interpretation.

Canonical page: https://skillsregistry.net/skills/taehojo-alphagenome-mcp  
JSON: https://api.skillsregistry.net/v1/skills/taehojo-alphagenome-mcp

## Description

Enables AI-powered genomic variant analysis including variant impact prediction, regulatory element discovery, and batch variant scoring. Currently operates in mock mode as a proof-of-concept awaiting the public release of Google DeepMind's AlphaGenome API.

## Trust

- **Trust score (0–1):** 0.95
- **Verification tier:** verified
- **Last scanned:** 2026-09-28

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** other
- **Updated:** 2026-09-28

## Source

- **Source listing:** [Glama](https://glama.ai/mcp/servers/s30nt9awk4)
- **Repository:** <https://github.com/taehojo/alphagenome-mcp>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "taehojo-alphagenome-mcp"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/taehojo-alphagenome-mcp` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/taehojo-alphagenome-mcp/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt