# AlphaFold Sovereign MCP

> Use this tool when you need to analyze biomedical data for variant clinical reporting, disease-target analysis, and drug repurposing. It integrates multiple data sources, including AlphaFold DB, to provide structural intelligence and inform clinical decisions. By using this tool, you can generate comprehensive reports and persist results to a local SQLite knowledge graph for further analysis.

Canonical page: https://skillsregistry.net/skills/smaniches-alphafold-sovereign-mcp  
JSON: https://api.skillsregistry.net/v1/skills/smaniches-alphafold-sovereign-mcp

## Description

Integrates AlphaFold DB and eight other biomedical data sources into MCP tools for variant clinical reporting, disease-target analysis, structural intelligence, and drug repurposing, with results persisted to a local SQLite knowledge graph.

## Trust

- **Trust score (0–1):** 0.00
- **Verification tier:** scanned
- **Last scanned:** 2026-09-01

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** database
- **Updated:** 2026-09-01

## Source

- **Source listing:** [Glama](https://glama.ai/mcp/servers/jkpg8xlgbk)
- **Repository:** <https://github.com/smaniches/alphafold-sovereign-mcp>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "smaniches-alphafold-sovereign-mcp"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/smaniches-alphafold-sovereign-mcp` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/smaniches-alphafold-sovereign-mcp/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt