# DepMap

> Use this tool when you need to analyze cancer dependency maps and identify therapeutic targets through CRISPR gene effect scores. It provides read-only access to DepMap data, allowing you to search gene symbols, compute aggregate metrics, and retrieve top cell-line dependencies. Ideal for bioinformatics workflows involving cancer research, this tool offers efficient data processing and access to the latest DepMap releases.

Canonical page: https://skillsregistry.net/skills/saurabhsing21-depmap  
JSON: https://api.skillsregistry.net/v1/skills/saurabhsing21-depmap

## Description

Provides read-only access to DepMap (Dependency Map) CRISPR gene effect scores through a local CSV cache. Offers four tools for searching gene symbols, computing aggregate dependency metrics, retrieving top cell-line dependencies ranked by gene effect values, and accessing dataset metadata. Built with pandas for efficient data processing and includes a download utility for fetching the latest DepMap releases. Designed for bioinformatics workflows involving cancer dependency analysis and therapeutic target identification.

## Trust

- **Trust score (0–1):** 0.98
- **Verification tier:** verified
- **Last scanned:** 2026-09-28

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** monitoring
- **Updated:** 2026-09-28

## Source

- **Source listing:** [PulseMCP](https://www.pulsemcp.com/servers/saurabhsing21-depmap)
- **Repository:** <https://github.com/saurabhsing21/deepmap-mcp>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "saurabhsing21-depmap"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/saurabhsing21-depmap` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/saurabhsing21-depmap/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt