# PocketScout

> Use this tool when you need to assess drug targets and predict binding site interactions, as it solves problems in target characterization, ligand discovery, and literature review by aggregating data from multiple sources and providing ranked recommendations through a unified workflow interface. It takes in target identifiers and returns comprehensive binding site intelligence, including related structures, ligand histories, and conservation data. Use PocketScout to streamline drug discovery workflows and inform binding site-focused research.

Canonical page: https://skillsregistry.net/skills/proprius-labs-pocketscout  
JSON: https://api.skillsregistry.net/v1/skills/proprius-labs-pocketscout

## Description

Provides binding site intelligence for drug target assessment by aggregating data from UniProt, PDB, AlphaFold, ChEMBL, and PubMed. Six tools compose into a scientific workflow: target characterization, related structure discovery, binding site mapping, ligand history analysis, conservation checking, and literature search. Includes an orchestration prompt for complete binding site assessments with ranked recommendations.

## Trust

- **Trust score (0–1):** 0.90
- **Verification tier:** verified
- **Last scanned:** 2026-09-28

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** ai-ml
- **Updated:** 2026-09-28

## Source

- **Source listing:** [PulseMCP](https://www.pulsemcp.com/servers/proprius-labs-pocketscout)
- **Repository:** <https://github.com/proprius-labs/pocketscout-mcp>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "proprius-labs-pocketscout"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/proprius-labs-pocketscout` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/proprius-labs-pocketscout/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt