# Solitarius MCP

> Solitarius MCP — preghosh-solitarius-mcp. Use this tool when you need to accelerate drug discovery through generative molecular design, leveraging advanced techniques like sampling, transfer learning, and reinforcement learning. The Solitarius MCP server provides a validated interface for large language models (LLMs) to access REINVENT4 operations, streamlining molecular analysis and design. Ideal for applications requiring efficient exploration of chemical space and optimization of molecular properties.

Canonical page: https://skillsregistry.net/skills/preghosh-solitarius-mcp  
JSON: https://api.skillsregistry.net/v1/skills/preghosh-solitarius-mcp

## Description

MCP server exposing REINVENT4 generative molecular-design operations as validated, LLM-callable tools for drug discovery, including sampling, transfer learning, reinforcement learning, and molecular analysis.

## Trust

- **Trust score (0–1):** 0.68
- **Verification tier:** scanned
- **Last scanned:** 2026-08-29

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** ai-ml
- **Updated:** 2026-08-29

## Source

- **Source listing:** [Glama](https://glama.ai/mcp/servers/wqucgxwpoz)
- **Repository:** <https://github.com/pregHosh/Solitarius-mcp>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "preghosh-solitarius-mcp"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/preghosh-solitarius-mcp` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/preghosh-solitarius-mcp/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt