# mcp-gprofiler

> mcp-gprofiler — pipeworx-io-mcp-gprofiler. Use this tool when you need to analyze a list of genes for functional enrichment against various databases, including GO, KEGG, and Reactome. It solves problems related to understanding gene function and identifying significant pathways, and accepts a list of gene IDs as input, producing enriched terms and pathways as output. Use it when working with genomic data to gain insights into biological processes and identify potential targets for further research.

Canonical page: https://skillsregistry.net/skills/pipeworx-io-mcp-gprofiler  
JSON: https://api.skillsregistry.net/v1/skills/pipeworx-io-mcp-gprofiler

## Description

g:Profiler (University of Tartu) — functional enrichment analysis for a gene list against GO, KEGG, Reactome, WikiPathways, TRANSFAC, miRTarBase, CORUM, HPA and HPO, plus gene/protein ID conversion and cross-species ortholog mapping. Keyless.

## Trust

- **Trust score (0–1):** 0.97
- **Verification tier:** verified
- **Last scanned:** 2026-09-28

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** container
- **Runtime environment:** vm
- **License:** MIT
- **Updated:** 2026-09-28

## Source

- **Source listing:** [GitHub](https://github.com/pipeworx-io/mcp-gprofiler)

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "pipeworx-io-mcp-gprofiler"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/pipeworx-io-mcp-gprofiler` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/pipeworx-io-mcp-gprofiler/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt