# Mutation Clinical Trial Matching MCP

> Use this tool when you need to find relevant clinical trials based on specific genetic mutations, solving the problem of manually searching through extensive databases. It takes natural language queries as input and outputs matching clinical trials from clinicaltrials.gov. Utilize this tool in contexts where precise clinical trial matching is crucial, such as medical research or patient care.

Canonical page: https://skillsregistry.net/skills/pickleton89-mutation-clinical-trial-matching-mcp  
JSON: https://api.skillsregistry.net/v1/skills/pickleton89-mutation-clinical-trial-matching-mcp

## Description

A Model Context Protocol server that enables Claude Desktop to search clinicaltrials.gov for matching clinical trials based on genetic mutations provided in natural language queries.

## Trust

- **Trust score (0–1):** 0.60
- **Verification tier:** unverified

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** search
- **Updated:** 2026-05-05

## Source

- **Source listing:** [Glama](https://glama.ai/mcp/servers/m2ay74pkyb)
- **Repository:** <https://github.com/pickleton89/mutation-clinical-trial-matching-mcp>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "pickleton89-mutation-clinical-trial-matching-mcp"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/pickleton89-mutation-clinical-trial-matching-mcp` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/pickleton89-mutation-clinical-trial-matching-mcp/pull`

---
SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt