# Open Targets

> Use this tool when you need to explore relationships between drugs, targets, and diseases, or to find evidence-backed associations between genes and diseases. It solves problems related to target identification, drug discovery, and disease research by providing access to genetics and literature-backed data. The tool takes search queries as input and returns relevant targets, diseases, and drugs as output.

Canonical page: https://skillsregistry.net/skills/opentargets  
JSON: https://api.skillsregistry.net/v1/skills/opentargets

## Description

Explore drug-target associations and disease-gene evidence. Search targets, diseases, and drugs with genetics and literature-backed data.

## Trust

- **Trust score (0–1):** 0.70
- **Verification tier:** unverified

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** search
- **Updated:** 2026-05-11

## Source

- **Source listing:** [Smithery](https://smithery.ai/server/opentargets)

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "opentargets"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/opentargets` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/opentargets/pull`

---
SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt