# openpgx

> Use this tool when you need to analyze genetic variant data for personalized drug responses and disease risk assessments. It solves problems related to pharmacogenomics by providing AI-driven insights into medication efficacy and health risks based on user genome data. The tool accepts natural language questions and user genome data as input, returning relevant information on drug responses and disease risks while ensuring privacy through local execution.

Canonical page: https://skillsregistry.net/skills/open-pgx-openpgx  
JSON: https://api.skillsregistry.net/v1/skills/open-pgx-openpgx

## Description

Enables AI-driven pharmacogenomic analysis by querying structured genetic variant, drug response, and disease risk data. Supports natural language questions about medications, traits, and health risks based on user genome data, with privacy-first local execution.

## Trust

- **Trust score (0–1):** 0.68
- **Verification tier:** scanned
- **Last scanned:** 2026-09-03

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** other
- **Updated:** 2026-09-03

## Source

- **Source listing:** [Glama](https://glama.ai/mcp/servers/yy2bk2q3hc)
- **Repository:** <https://github.com/open-pgx/openpgx>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "open-pgx-openpgx"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/open-pgx-openpgx` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/open-pgx-openpgx/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt