# NexOnco (CIViC Precision Oncology)

> Use this tool when you need to analyze clinical evidence data in precision oncology research, connecting genetic variants to cancer treatments through flexible search and detailed reporting. It solves problems in researching disease-therapy relationships, molecular profiles, and phenotypes by providing summary statistics, top evidence entries, and literature citations. The tool takes in search queries and returns detailed reports, making it ideal for researchers in precision oncology.

Canonical page: https://skillsregistry.net/skills/nexgene-civic-oncology  
JSON: https://api.skillsregistry.net/v1/skills/nexgene-civic-oncology

## Description

Nexonco-MCP is an advanced server for accessing and analyzing clinical evidence data in precision oncology research. Developed by Nexgene Research, this Python implementation connects to the CIViC (Clinical Interpretation of Variants in Cancer) GraphQL API, providing flexible search capabilities across diseases, therapies, molecular profiles, and phenotypes. The server exposes a single tool that returns detailed reports containing summary statistics, top evidence entries, and literature citations, making it particularly valuable for researchers exploring relationships between genetic variants and cancer treatments. The implementation supports both Claude Desktop and NANDA server configurations, with Docker containerization available for easy deployment.

## Trust

- **Trust score (0–1):** 0.99
- **Verification tier:** verified
- **Last scanned:** 2026-09-28

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** cloud-infra
- **Updated:** 2026-09-28

## Source

- **Source listing:** [PulseMCP](https://www.pulsemcp.com/servers/nexgene-civic-oncology)
- **Repository:** <https://github.com/nexgene-research/nexonco-mcp>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "nexgene-civic-oncology"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/nexgene-civic-oncology` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/nexgene-civic-oncology/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt