# Rosetta MCP

> Use this tool when you need to perform protein modeling and design tasks, such as structure refinement, mutation analysis, and docking, with ease using natural language commands. The Rosetta MCP tool solves problems in protein engineering and design by providing a user-friendly interface to the Rosetta suite via Docker. It takes in natural language inputs and outputs refined protein models and analysis results, making it ideal for bioinformatics and computational biology applications.

Canonical page: https://skillsregistry.net/skills/macromnex-rosetta-mcp  
JSON: https://api.skillsregistry.net/v1/skills/macromnex-rosetta-mcp

## Description

Enables protein modeling and design using the Rosetta suite via Docker, including structure refinement, mutation stability analysis, docking, and loop modeling through natural language commands.

## Trust

- **Trust score (0–1):** 0.69
- **Verification tier:** scanned
- **Last scanned:** 2026-08-31

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** cloud-infra
- **Updated:** 2026-08-31

## Source

- **Source listing:** [Glama](https://glama.ai/mcp/servers/jx0tezp5dw)
- **Repository:** <https://github.com/MacromNex/rosetta_mcp>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "macromnex-rosetta-mcp"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/macromnex-rosetta-mcp` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/macromnex-rosetta-mcp/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt