# PubChem MCP Server

> Use this tool when you need to retrieve detailed chemical compound information, such as structures and physical properties, from the PubChem database. It solves problems related to chemical analysis by providing access to molecular data through querying by compound names, SMILES notation, or CIDs. The tool takes in queries as input and returns detailed molecular data as output, making it ideal for use cases involving chemical research and analysis.

Canonical page: https://skillsregistry.net/skills/jackkuo666-pubchem-mcp-server  
JSON: https://api.skillsregistry.net/v1/skills/jackkuo666-pubchem-mcp-server

## Description

Enables AI assistants to search and retrieve chemical compound information, structures, and physical properties from the PubChem database. It supports querying via compound names, SMILES notation, or CIDs to provide detailed molecular data for chemical analysis.

## Trust

- **Trust score (0–1):** 0.94
- **Verification tier:** verified
- **Last scanned:** 2026-09-19

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** database
- **Updated:** 2026-09-19

## Source

- **Source listing:** [Glama](https://glama.ai/mcp/servers/eyyl2bl20f)
- **Repository:** <https://github.com/JackKuo666/PubChem-MCP-Server>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "jackkuo666-pubchem-mcp-server"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/jackkuo666-pubchem-mcp-server` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/jackkuo666-pubchem-mcp-server/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt