# CIViC MCP Server

> Use this tool when you need to query clinical interpretations of cancer variants or retrieve evidence and assertions for specific variants. It solves problems related to cancer genomics and precision medicine by providing access to the CIViC database through APIs like get_variant_evidence and get_variant_assertions. This tool accepts variant identifiers as input and returns relevant clinical interpretations and evidence as output.

Canonical page: https://skillsregistry.net/skills/griffithlab-civic-mcp-server  
JSON: https://api.skillsregistry.net/v1/skills/griffithlab-civic-mcp-server

## Description

Enables querying the CIViC database for clinical interpretations of cancer variants through tools like get_variant_evidence and get_variant_assertions.

## Trust

- **Trust score (0–1):** 0.69
- **Verification tier:** scanned
- **Last scanned:** 2026-08-31

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** database
- **Updated:** 2026-08-31

## Source

- **Source listing:** [Glama](https://glama.ai/mcp/servers/tces7g579f)
- **Repository:** <https://github.com/griffithlab/civic-mcp-server>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "griffithlab-civic-mcp-server"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/griffithlab-civic-mcp-server` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/griffithlab-civic-mcp-server/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt