# Goodfire EVEE

> Use this tool when you need to analyze genomic variants and predict their effects on biological functions. The Goodfire EVEE server provides access to six tools that deliver interpretable variant effect predictions, clinical summaries, and disruption profiles, solving problems in genomics and precision medicine. It takes genetic variants as input and outputs AI-generated clinical summaries and pathogenicity predictions, making it ideal for use cases involving variant interpretation and prioritization.

Canonical page: https://skillsregistry.net/skills/goodfire-evee  
JSON: https://api.skillsregistry.net/v1/skills/goodfire-evee

## Description

The Goodfire EVEE MCP server provides six tools for accessing Goodfire AI's EVEE API, which delivers interpretable variant effect predictions for genomic variants using the Evo 2 genomic foundation model. Tools support searching genetic variants, retrieving AI-generated clinical summaries with mechanistic interpretations, and analyzing disruption profiles across biological annotations. Pre-computed pathogenicity predictions are available for 4.2 million ClinVar variants.

## Trust

- **Trust score (0–1):** 0.64
- **Verification tier:** scanned
- **Last scanned:** 2026-09-01

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** search
- **Updated:** 2026-09-01

## Source

- **Source listing:** [PulseMCP](https://www.pulsemcp.com/servers/goodfire-evee)
- **Repository:** <https://github.com/goodfire-ai/evee-mcp>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "goodfire-evee"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/goodfire-evee` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/goodfire-evee/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt