# Noctua MCP Server

> Use this tool when you need to create, edit, and query biological knowledge models, specifically Gene Ontology Causal Activity Models (GO-CAMs). It solves problems related to biological knowledge representation, causal pathway construction, and evidence-based modeling. The Noctua MCP Server accepts inputs through the Barista API and outputs edited models, supporting use cases in bioinformatics and systems biology research.

Canonical page: https://skillsregistry.net/skills/geneontology-noctua-mcp  
JSON: https://api.skillsregistry.net/v1/skills/geneontology-noctua-mcp

## Description

Enables editing and querying of Gene Ontology Causal Activity Models (GO-CAMs) through the Barista API. Supports model creation, individual and fact management, evidence addition, and causal pathway construction for biological knowledge representation.

## Trust

- **Trust score (0–1):** 0.60
- **Verification tier:** unverified

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** other
- **Updated:** 2026-04-29

## Source

- **Source listing:** [Glama](https://glama.ai/mcp/servers/iwfbgk56vu)
- **Repository:** <https://github.com/geneontology/noctua-mcp>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "geneontology-noctua-mcp"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/geneontology-noctua-mcp` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/geneontology-noctua-mcp/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt
