# Helix

> Helix — coindef-helix. Use this tool when you need to design and optimize gene-editing workflows with precision and reproducibility. Helix solves problems in genetic engineering by providing a declarative DSL and compiler that generates reliable designs, and its interface allows for input of genetic sequences and output of optimized editing plans. It integrates with git for version control and can be driven by any AI agent through its LLM agents and MCP server.

Canonical page: https://skillsregistry.net/skills/coindef-helix  
JSON: https://api.skillsregistry.net/v1/skills/coindef-helix

## Description

A declarative DSL and compiler for reproducible gene-editing design — with LLM agents and an MCP server so any AI agent can drive it safely.

## Trust

- **Trust score (0–1):** 0.92
- **Verification tier:** verified
- **Last scanned:** 2026-09-28

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** container
- **Runtime environment:** vm
- **License:** Apache-2.0
- **Updated:** 2026-09-28

## Source

- **Source listing:** [GitHub](https://github.com/coindef/Helix)

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "coindef-helix"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/coindef-helix` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/coindef-helix/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt