# heracleum-tox-mcp-server

> Use this tool when you need to predict the toxicological profile of Heracleum sosnowskyi metabolites, classify their toxicity, or estimate synthesis costs. It takes chemical structures as input and outputs LD50 predictions, toxicity classifications, and synthesis cost estimates. Ideal for use in toxicology research, chemical safety assessment, and drug discovery applications.

Canonical page: https://skillsregistry.net/skills/chemagents-heracleum-tox-mcp-server  
JSON: https://api.skillsregistry.net/v1/skills/chemagents-heracleum-tox-mcp-server

## Description

Reproduces the in-silico toxicological profile of Heracleum sosnowskyi metabolites from Rassabina & Fedorov (2025) using open-source models for LD50 prediction, toxicity classification, chemical space clustering, and synthesis cost estimation.

## Trust

- **Trust score (0–1):** 0.66
- **Verification tier:** scanned
- **Last scanned:** 2026-08-30

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** file-system
- **Updated:** 2026-08-30

## Source

- **Source listing:** [Glama](https://glama.ai/mcp/servers/amxi4d5jec)
- **Repository:** <https://github.com/chemagents/heracleum-tox-mcp-server>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "chemagents-heracleum-tox-mcp-server"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/chemagents-heracleum-tox-mcp-server` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/chemagents-heracleum-tox-mcp-server/pull`

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