# spliceailookup-link

> spliceailookup-link — berntpopp-spliceailookup-link. Use this tool when you need to predict the impact of genetic variants on splicing or resolve variant information. It provides SpliceAI, Pangolin, and SpliceAI-10k predictions, as well as Ensembl VEP-backed variant resolution, taking in variant data and returning detailed impact predictions. Ideal for genomic analysis and research applications, it streamlines the process of understanding variant effects on gene expression.

Canonical page: https://skillsregistry.net/skills/berntpopp-spliceailookup-link  
JSON: https://api.skillsregistry.net/v1/skills/berntpopp-spliceailookup-link

## Description

MCP server for SpliceAI Lookup (Broad Institute): SpliceAI, Pangolin and SpliceAI-10k splice-impact predictions for variants, plus an Ensembl VEP-backed variant resolver.

## Trust

- **Trust score (0–1):** 0.77
- **Verification tier:** verified
- **Last scanned:** 2026-09-28

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** container
- **Runtime environment:** vm
- **License:** MIT
- **Updated:** 2026-09-28

## Source

- **Source listing:** [GitHub](https://github.com/berntpopp/spliceailookup-link)

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "berntpopp-spliceailookup-link"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/berntpopp-spliceailookup-link` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/berntpopp-spliceailookup-link/pull`

---
SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt