# hpo-link

> Use this tool when you need to query and explore the Human Phenotype Ontology (HPO) for term lookup, hierarchy exploration, and associations with genes and diseases. It solves problems related to understanding complex phenotypic relationships and provides fast offline lookups through a local SQLite database. The hpo-link tool takes in queries and returns relevant HPO terms, mappings, and associations, making it ideal for biomedical research and analysis.

Canonical page: https://skillsregistry.net/skills/berntpopp-hpo-link  
JSON: https://api.skillsregistry.net/v1/skills/berntpopp-hpo-link

## Description

MCP server that provides tools for querying the Human Phenotype Ontology (HPO) including term lookup, hierarchy exploration, cross-ontology mappings, and gene-phenotype-disease associations, all grounded in a local SQLite database for fast offline lookups.

## Trust

- **Trust score (0–1):** 0.41
- **Verification tier:** scanned
- **Last scanned:** 2026-08-31

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** database
- **Updated:** 2026-08-31

## Source

- **Source listing:** [Glama](https://glama.ai/mcp/servers/tfyrxspbyp)
- **Repository:** <https://github.com/berntpopp/hpo-link>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "berntpopp-hpo-link"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/berntpopp-hpo-link` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/berntpopp-hpo-link/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt