# PubChem MCP Server

> Use this tool when you need to search, analyze, and retrieve information on chemical compounds, solving problems related to chemical research, drug discovery, and safety assessments. It provides access to a vast database of over 110 million compounds, accepting chemical structures, names, or identifiers as inputs and returning relevant data on properties, bioassays, and safety. Ideal for use in scientific research, pharmaceutical development, and chemical safety evaluations.

Canonical page: https://skillsregistry.net/skills/augmented-nature-pubchem-mcp-server  
JSON: https://api.skillsregistry.net/v1/skills/augmented-nature-pubchem-mcp-server

## Description

Provides access to over 110 million chemical compounds with tools for chemical search, structure analysis, property calculation, bioassay data retrieval, and safety information through the PubChem database.

## Trust

- **Trust score (0–1):** 0.97
- **Verification tier:** verified
- **Last scanned:** 2026-09-28

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** database
- **Updated:** 2026-09-28

## Source

- **Source listing:** [Glama](https://glama.ai/mcp/servers/djlanj1nvz)
- **Repository:** <https://github.com/Augmented-Nature/PubChem-MCP-Server>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "augmented-nature-pubchem-mcp-server"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/augmented-nature-pubchem-mcp-server` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/augmented-nature-pubchem-mcp-server/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt