# GTEx Portal

> Use this tool when you need to analyze human gene expression data across tissues, perform genetic association analysis, or retrieve dataset metadata. The GTEx Portal provides programmatic access to a large genomics dataset through 25 specialized tools, accepting inputs such as gene queries and variant lookups, and outputting expression profiles, association results, and dataset information. It is ideal for genomics researchers, bioinformaticians, and AI assistants working with human genomics data who require robust and efficient data analysis capabilities.

Canonical page: https://skillsregistry.net/skills/augmented-nature-gtex-portal  
JSON: https://api.skillsregistry.net/v1/skills/augmented-nature-gtex-portal

## Description

This TypeScript-based MCP server provides access to GTEx (Genotype-Tissue Expression) genomics data through 25 specialized tools organized into expression analysis, association analysis, and reference/dataset categories. Built with comprehensive TypeScript type definitions and a robust API client that handles GTEx Portal API v2 communication, it offers tools for gene expression profiling across tissues, eQTL/sQTL genetic association analysis, variant lookups, and dataset metadata retrieval with features like error handling, pagination, and parameter validation. The implementation targets genomics researchers, bioinformaticians, and AI assistants working with human gene expression data who need programmatic access to one of the largest publicly available genomics datasets for tissue-specific expression analysis, genetic variant associations, and comparative genomics studies.

## Trust

- **Trust score (0–1):** 0.50
- **Verification tier:** unverified

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** search
- **Updated:** 2026-04-28

## Source

- **Source listing:** [PulseMCP](https://www.pulsemcp.com/servers/augmented-nature-gtex-portal)
- **Repository:** <https://github.com/augmented-nature/gtex-mcp-server>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "augmented-nature-gtex-portal"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/augmented-nature-gtex-portal` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/augmented-nature-gtex-portal/pull`

---
SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt