# Rosetta Protein Modeling

> Use this tool when you need to model and analyze protein structures, design new proteins, or predict structural properties. It solves problems in computational biology, such as understanding protein function and behavior, by providing a comprehensive framework for structure prediction and analysis. The tool takes in sequence and structure data and outputs modeled protein structures and analysis results, requiring a local Rosetta installation to run workflows.

Canonical page: https://skillsregistry.net/skills/arielbs-rosetta-mcp  
JSON: https://api.skillsregistry.net/v1/skills/arielbs-rosetta-mcp

## Description

Provides protein structure modeling and analysis via the Rosetta and PyRosetta computational biology frameworks, with Biotite integration for sequence and structure translation. Enables AI agents to run protein design, structure prediction, and analysis workflows. Requires a local Rosetta installation.

## Trust

- **Trust score (0–1):** 0.67
- **Verification tier:** scanned
- **Last scanned:** 2026-09-28

## Facts

- **Version:** 1.0.0
- **Skill type:** atomic
- **Execution layer:** mcp-remote
- **Runtime environment:** api
- **Category:** ai-ml
- **Updated:** 2026-09-28

## Source

- **Source listing:** [PulseMCP](https://www.pulsemcp.com/servers/arielbs-rosetta-mcp)
- **Repository:** <https://github.com/arielbs/rosetta-mcp-server>

## Use it

Resolve this record through the SkillsRegistry MCP server (no auth, read-only):

```
claude mcp add --transport http --scope user skillsregistry https://api.skillsregistry.net/mcp
```

```json
{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "get_skill",
    "arguments": {
      "slug": "arielbs-rosetta-mcp"
    }
  }
}
```

REST: `GET https://api.skillsregistry.net/v1/skills/arielbs-rosetta-mcp` · pull for local use: `GET https://api.skillsregistry.net/v1/skills/arielbs-rosetta-mcp/pull`

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SkillsRegistry indexes agent skills from public registries and GitHub. Skills we have analysed are scanned with Circle-IR and scored on six dimensions; each listing states its scan coverage. More: https://skillsregistry.net/llms.txt